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Cardiologists Comment on Aspirin Versus Resveratrol

Friday, April 16th, 2010

With the realization that half of the people experiencing a sudden mortal heart attack were taking aspirin on the day of their demise, and the fact that higher-than-recommended doses of aspirin are needed to prevent blood clot formation in coronary arteries, coupled with an announcement that the red wine molecule, Resveratrol may protect from sudden mortal heart attack in a superior fashion to aspirin, suggests re-evaluation of cardiology’s current instruction regarding prevention of heart attacks, says Nate Lebowitz MD, cardiologist with the Advanced Cardiology Institute in Ft. Lee, New Jersey.

In a presentation at a National Institutes of Health symposium in Washington DC today, University of Connecticut researchers showed resveratrol limits damage caused by a heart attack, prevents sudden cardiac death in animals, and is “the best yet devised method of cardioprotection.”

Read more on PR Newswire

NF-kappaB inhibitory action of resveratrol: A probable mechanism of neuroprotection in experimental diabetic neuropathy.

Thursday, April 15th, 2010

Resveratrol has shown array of biological actions, and is under clinical development for various disease conditions. The etiology of diabetic neuropathy revolves around oxidative stress, AGE formation, lipid peroxidation etc.
All these stimulate inflammatory processes and NF-kappaB cascade is considered as one of the major players of inflammatory response. Activation of NF-kappaB results in elevated levels of inflammatory mediators. COX-2 and TNF-alpha activity have also been correlated with inflammatory damage in the pathophysiology of diabetic neuropathy (DN).

New Report Examines H1N1 Flu and Pregnancy

Monday, April 12th, 2010

Delays in seeking and obtaining appropriate care for the H1N1 pandemic flu may have played a role in the rapid clinical decline of several pregnant and postpartum women in New York City last year, the CDC said.

A case series of 17 women with severe H1N1 disease showed that few were treated quickly with oseltamivir (Tamiflu), and only one had been vaccinated against the pandemic flu, the agency reported in the March 26 issue of the Morbidity and Mortality Weekly Report.

Read more on Med Page Today.

China faces ‘diabetes epidemic’, research suggests

Sunday, April 11th, 2010

China faces a diabetes epidemic, with almost one in 10 adults having the disease while most cases remain undiagnosed, researchers have said.

Tests showed diabetes was more endemic than previously thought, according to the New England Journal of Medicine. The figures suggest China has some 90 million diabetics, far more than India.

Rapid economic growth has affected public health, through urbanisation, changed diets and more sedentary lifestyles, researchers said.

Rigorous new tests suggested that more than 92 million Chinese adults had diabetes and that nearly 150 million more were showing early symptoms, researchers said.

Read more on the BBC

Finding A Potential New Target for Treating Rheumatoid Arthritis

Saturday, April 10th, 2010

By enhancing the activity of immune cells that protect against runaway inflammation, researchers at NYU Langone Medical Center may have found a novel therapy for rheumatoid arthritis and other autoimmune diseases. In a new study published in the March 25, 2010 online edition of Science, the researchers reveal how treating these immune cells with an investigational drug wards off inflammation by holding a particular enzyme at bay.

“This is an unusual mechanism that could provide a potential therapeutic approach for the treatment of autoimmune diseases like rheumatoid arthritis or inflammatory diseases like Crohn’s disease,” says Michael Dustin, PhD, the Irene Diamond Professor of Immunology and professor of pathology at NYU Langone Medical Center.

Read more on Newswise

Kidney Disease Hides in People with Undiagnosed Diabetes

Friday, April 9th, 2010

Millions of Americans may have chronic kidney disease (CKD) and not know it, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN).

“Our research indicates that much of the CKD burden in the United States is in persons with prediabetes and undiagnosed diabetes, who are not being screened for CKD,” comments Laura C. Plantinga, ScM (University of California, San Francisco). The researchers believe that broader screening may be needed to detect patients with these two “relatively silent yet harmful diseases.”

Read more on Newswise

Statement From American Heart Association President Clyde Yancy, M.D. On Senate Agricultural Committee Markup Of Child Nutrition Act

Friday, April 9th, 2010

Calorie-packed snacks and sugary beverages combined with sedentary behaviors are fueling the obesity crisis among our nation’s youth and threatening our future health and prosperity as a country. Not only does childhood obesity lead to abnormal cholesterol and hypertension in kids, but it can potentially increase the risk of diabetes and heart disease in early adulthood.

Currently, only 21 percent of children and adolescents eat the recommended five or more servings of fruits and vegetables each day. And studies have shown that a healthier child learns more effectively and achieves more academically. We are losing a generation to childhood obesity.

Read more on Medical News Today

A sweet problem: Princeton researchers find that high-fructose corn syrup prompts considerably more weight gain

Wednesday, April 7th, 2010

A Princeton University research team has demonstrated that all sweeteners are not equal when it comes to weight gain: Rats with access to high-fructose corn syrup gained significantly more weight than those with access to table sugar, even when their overall caloric intake was the same.

In addition to causing significant weight gain in lab animals, long-term consumption of high-fructose corn syrup also led to abnormal increases in body fat, especially in the abdomen, and a rise in circulating blood fats called triglycerides. The researchers say the work sheds light on the factors contributing to obesity trends in the United States.

Read more on the Princeton University website.

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